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Informative value of laboratory markers in assessing the stage of liver fibrosis in children with type 1 autoimmune hepatitis

https://doi.org/10.53529/2500-1175-2023-1-53-55

About the Authors

O. V. Kurbatova
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



G. B. Movsisyan
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



S. V. Petrichuk
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



D. V. Parakhina
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



D. S. Demyanov
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



D. G. Kuptsova
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



T. V. Radygina
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



E. L. Semikina
National Medical Research Center for Children’s Health; Sechenov First Moscow State Medical University
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1
119991, Moscow, st. Trubetskaya, d. 8, building 2,



A. S. Potapov
National Medical Research Center for Children’s Health; Sechenov First Moscow State Medical University
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1
119991, Moscow, st. Trubetskaya, d. 8, building 2,



E. V. Freidlin
National Medical Research Center for Children’s Health
Russian Federation

119991, Moscow, Lomonosovsky prospect, 2, building 1



References

1. Vuerich M, Wang N, Kalbasi A, Graham JJ, Longhi MS. Dysfunctional Immune Regulation in Autoimmune Hepatitis: From Pathogenesis to Novel Therapies. Front Immunol. 2021 Sep 28; 12: 746436. https://doi.org/10.3389/fimmu.2021.746436.

2. Sirbe C, Simu G, Szabo I, Grama A, Pop TL. Pathogenesis of Autoimmune Hepatitis-Cellular and Molecular Mechanisms. Int J Mol Sci. 2021 Dec 17; 22 (24): 13578. https://doi.org/10.3390/ijms222413578.

3. Patel AM, Liu YS, Davies SP, Brown RM, Kelly DA, Scheel-Toellner D, Reynolds GM, Stamataki Z. The Role of B Cells in Adult and Paediatric Liver Injury. Front Immunol. 2021 Sep 23; 12: 729143. https://doi.org/10.3389/fimmu.2021.729143.

4. Li Y, Yan L, Wang R, Wang Q, You Z, Li B, Zhang J, Huang B, Chen Y, Li Y, Lian M, Tang R, Qiu D, Gershwin ME, Xiao X, Miao Q, Ma X. Serum Immunoglobulin G Levels Predict Biochemical and Histological Remission of Autoimmune Hepatitis Type 1: A Single-Center Experience and Literature Review. Clin Rev Allergy Immunol. 2022 Apr; 62 (2): 292–300. https://doi.org/10.1007/s12016-021-08833-w.

5. Wang P, Wang Y, Liu H, Han X, Yi Y, Wang X, Li X. Role of triglycerides as a predictor of autoimmune hepatitis with cirrhosis. Lipids Health Dis. 2022 Oct 25; 21 (1): 108. https://doi.org/10.1186/s12944-022-01716-9.

6. Biewenga M, Verhelst X, Baven-Pronk M, Putter H, van den Berg A, Colle I, Schouten J, Sermon F, Van Steenkiste C, van Vlierberghe H, van der Meer A, van Hoek B; Dutch Autoimmune Hepatitis Study Group. Aminotransferases During Treatment Predict Long-Term Survival in Patients With Autoimmune Hepatitis Type 1: A Landmark Analysis. Clin Gastroenterol Hepatol. 2022 Aug; 20 (8): 1776–1783.e4. https://doi.org/10.1016/j.cgh.2021.05.024.

7. Pan Y, Yang K, Sun B, Chen J, Tian P. Application of alkaline phosphatase to platelet ratio as a novel noninvasive index predicts liver fibrosis in patients with chronic hepatitis B. Exp Ther Med. 2022 Aug 9; 24 (4): 619. https://doi.org/10.3892/etm.2022.11556.

8. Harrington C, Krishnan S, Mack CL, Cravedi P, Assis DN, Levitsky J. Noninvasive biomarkers for the diagnosis and management of autoimmune hepatitis. Hepatology. 2022 Dec; 76 (6): 1862–1879. https://doi.org/10.1002/hep.32591.

9. Kulebina EA, Surkov AN, Kulikov KA, Potapov AS, Bessonov EE. Validaciya pokazatelej tranzientnoj elastografii dlya ocenki stadii fibroza pecheni u detej. Lechashchij Vrach. 2020; 8: 57–60. (In Russ.) https://doi.org/10.26295/OS.2020.26.84.00.


Review

For citations:


Kurbatova O.V., Movsisyan G.B., Petrichuk S.V., Parakhina D.V., Demyanov D.S., Kuptsova D.G., Radygina T.V., Semikina E.L., Potapov A.S., Freidlin E.V. Informative value of laboratory markers in assessing the stage of liver fibrosis in children with type 1 autoimmune hepatitis. Allergology and Immunology in Paediatrics. 2023;(1):53-55. (In Russ.) https://doi.org/10.53529/2500-1175-2023-1-53-55

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ISSN 2500-1175 (Print)
ISSN 2712-7958 (Online)