Clinical-immunological parallels in chronic renal Failure in children
https://doi.org/10.24411/2500-1175-2020-10006
Abstract
Chronic renal failure (CRF) remains an important problem in childhood. We have studied patients with chronic kidney disease (CKD) at the 3–5 stages at the stages of conservative treatment, dialysis therapy and kidney transplantation (n=72). The main reason for development is defined CRF in children — CAKUT-syndrome. The main clinical-anamnestic features at different stages of CKD are shown. Clinical-immunological correlations were carried out, hypoimmune state of both cellular and humoral links of immunity was detected in CRF.
About the Authors
G. A. MakovetskayaRussian Federation
Samara
O. V. Borisova
Russian Federation
Olga V. Borisova - doctor of medical sciences, professor of the Department of Childhood Infections of Samara State Medical University of the Ministry of Health of the Russian Federation.
89, Chapayevskaya Str., Samara, 443099
L. I. Mazur
Russian Federation
Samara
I. V. Barinov
Russian Federation
Samara
References
1. Здравоохранение в России. 2019: Статистический сборник / Росстат. М.: 2019. 170 с.
2. KDIGO 2012 Clinical practice guideline for the evaluation and management of chronic kidney disease // Kidney Int. (Suppl.). 2013. №3. Р. 41–150.
3. Роль некоторых генетических факторов в прогрессировании хронической болезни почек у детей / Г.А. Маковецкая, О.А. Седашкина, Д.В. Печкуров // Практическая медицина. 2015. №7 (92). С.72–76.
4. Раннее выявление прогрессирования хронической болезни почек: стандартные и модифицированные методы диагностики / Борисова О.В., Терехин С.С., Маковецкая Г.А., Мазур Л.И., Баринов И.В. // Педиатрия. Журнал им. Г.Н. Сперанского. 2012. Т. 91, № 6. С. 50–54.
5. Базовые понятия аллергологии (часть 2) / Грищенко Е.А. // Аллергология и иммунология в педиатрии. 2017. №1 (48). С. 36–48.
6. Иммунологические нарушения у пациентов с хронической болезнью почек. Перспективы иммуно-заместительной терапии / С.И. Сокуренко, А.Н. Федосеев, Т.В. Борисова // Клиническая практика. 2014. № 3. С. 83–88.
7. Other Blood and Immune Disorders in Chronic Kidney Disease /Walter H.Hцrl // Comprehensive Clinical Nephrology (Fourth Edition). 2020. Р. 959–968. https://doi.org/10.1016/B978-0-323-05876-6.00080-0 (дата обращения 05.03.2020).
8. IL-10, IL-6, and TNF-alpha: central factors in the altered cytokine network of uremia – the good, the bad, and the ugly / Stenvinkel P., Ketteler M., Johnson R.J., Lindholm B., Pecoits-Filho R., et al // Kidney Int. 2005. 67: 1216–1233.
9. KDOQI. Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratification. Am J Kidney Dis. 2002. T. 2 Suppl. 1. P. 1–246.
10. Chronic kidney disease in children / Francesca Becherucci, Rosa Maria Roperto, Marco Materassi, and Paola Romagnani // Clin Kidney J. 2016. № 9 (4). Р. 583–591.
Review
For citations:
Makovetskaya G.A., Borisova O.V., Mazur L.I., Barinov I.V. Clinical-immunological parallels in chronic renal Failure in children. Allergology and Immunology in Paediatrics. 2020;(2):41-48. (In Russ.) https://doi.org/10.24411/2500-1175-2020-10006