Comparison of vaccination coverage of children of the first year of life in the pre-pandemic period and during the COVID-19 pandemic
https://doi.org/10.53529/2500-1175-2025-1-40-49
Abstract
Introduction. Vaccination remains the most effective measure to combat infectious diseases. The COVID-19 pandemic has made adjustments to the work of pediatric health services around the world, which has affected all aspects of life, including routine immunization of children.
Objective. To analyze the indicators of coverage and timeliness of vaccination of children of the first year of life in the pre-pandemic period and during the COVID-19 pandemic, to assess the frequency and severity of post-vaccination reactions in children of the first year of life.
Materials and methods. A retrospective single-center study of medical documentation (form 112/y) of 414 children was conducted on the basis of GBU RO “City Children’s Polyclinic No. 3” in Ryazan, who were divided into 2 groups: group 1 — children born in 2018 (n = 256), among whom 47.5% (n = 122) were girls, 51.5% (n = 134) are boys, group 2 are children born in 2020 (n = 158), of which 49% (n = 77) are girls, 51% (n = 81) are boys. The assessment of intergroup differences was carried out using the Pearson criterion (χ2), adjusted for small samples. The difference in values was considered statistically significant at p < 0.05.
Results. Vaccination coverage in 2018 and 2020 was 95% and 98%, respectively (p < 0.05). The post-vaccination period in the majority of vaccinated children in group 1 (85%, n = 208) and in group 2 (81%, n = 128) proceeded smoothly (p = 0.04).
Conclusion. The COVID-19 pandemic did not have a negative impact on routine vaccination in the population of children in the first year of life.
About the Authors
N. A. BelykhRussian Federation
Natalia Anatolyevna Belykh — Dr. Sci., Associate Professor, Head of the Department of Faculty and Polyclinic Pediatrics with the course of Pediatrics of the FDPO
390026, Ryazan, Vysokovoltnaya str., 9
P. O. Kotova
Russian Federation
Polina Olegovna Kotova — first-year resident in pediatrics at the Department of Faculty and Polyclinic Pediatrics with a course in pediatrics of the FDPO
390026, Ryazan, Vysokovoltnaya str., 9
I. V. Pisnyur
Russian Federation
Inna Vladimirovna Pisnyur — Assistant of the Department of Faculty and Polyclinic Pediatrics with the course of Pediatrics of the FDPO
390026, Ryazan, Vysokovoltnaya str., 9
E. V. Stezhkina
Russian Federation
Elena Viktorovna Stezhkina — Cand. Sci., Associate Professor of the Department of Faculty and Polyclinic Pediatrics with a course in Pediatrics of the FDPO
390026, Ryazan, Vysokovoltnaya str., 9
References
1. Girina A.A., Zaplatnikov A.L., Petrovsky F.I. Vaccination of children within the framework of the national calendar of preventive vaccinations during the COVID-19 pandemic: problems and solutions. Russian medical journal. Mother and child. 2021; 4 (1): 85–89. (In Russ.) https://doi.org/10.32364/2618-8430-2021-4-1-85-89.
2. Shukla V.V., Shah R.C. Vaccinations in Primary Care. Indian J Pediatr. 2018; 85 (12):1118–1127. https://doi.org/10.1007/s12098-017-2555-2.
3. Hill H.A., Chen M., Elam-Evans L.D., et al. Vaccination Coverage by Age 24 Months Among Children Born During 2018–2019 — National Immunization Survey–Child, United States, 2019–2021. MMWR Morb Mortal Wkly Rep. 2023; 72: 33–38. https://doi.org/10.15585/mmwr.mm7202a3.
4. Shirokostup S.V., Lukyanenko N.V., Saldan I.P. Epidemiological analysis of the incidence of tick-borne viral encephalitis in the rural population of the Siberian Federal District. Eruditio Juvenium. 2019; 7 (4): 518–525. https://doi.org/10.23888/HMJ201974518-525.
5. Olusanya O.A., Bednarczyk R.A., Davis R.L. et al. Addressing Parental Vaccine Hesitancy and Other Barriers to Childhood/Adolescent Vaccination Uptake During the Coronavirus (COVID-19) Pandemic. Front. Immunol. 2021; 12. https://doi.org/10.3389/fimmu.2021.663074.
6. Wang W., Zhang X.X., Zhang Z.N., et al. Trust in vaccination and its influencing factors among parents of children aged 0–6 years. Zhonghua Yu Fang Yi Xue Za Zhi. 2022; 56 (12): 1821–1827. https://doi.org/10.3760/cma.j.cn112150-20220211-00124.
7. Faksová K., Laksafoss A.D., Hviid A. COVID-19 vaccines and adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals. Vaccine. 2024; 42 (9): 2200–2211. https://doi.org/10.1016/j.vaccine.2024.01.100.
8. Ackerson B.K., Sy L.S., Glenn S.C., et al. Pediatric Vaccination During the COVID-19 Pandemic. Pediatrics. 2021; 148 (1): e2020047092. https://doi.org/10.1542/peds.2020-047092.
9. Buchy P, Badur S. Who and when to vaccinate against influenza. Int J Infect Dis. 2020; 93: 375–387. https://doi.org/10.1016/j.ijid.2020.02.040.
10. Domingues C.M.A.S., Teixeira A.M.D.S., Moraes J.C. Vaccination coverage in children in the period before and during the COVID-19 pandemic in Brazil: a time series analysis and literature review. Jornal de Pediatria. 2023; 99 (1): 12–21. https://doi.org/10.1016/j.jped.2022.11.004.
11. Diallo M., Dicko I., Dembele S. et al. Comparing vaccination coverage before and during COVID-19 pandemic in children under one year in the health district of commune V in Bamako, Mali. BMC Pediatrics. 2023; 23: 599. https://doi.org/10.1186/s12887-023-04416-0.
12. Namazova-Baranova L.S., Fedoseenko M.V., Grinchik P.R., Girina A.A., Kovalev S.V., Mazokha A.V., Makushina E.D., Malinina E.I., Musikhina A.Yu., Perminova O.A., Plenskovskaya N.Y., Privalova T.E., Rychkova O.A., Semerikov V.V., Fominykh M.V., Fugol D.S., Yakimova N.V., Rtishchev A.Yu., Rusinova D.S. Immunization and Immunization Coverage According to National Immunization Schedule for Children Population: Cross-Sectional Multi-Centre Study. Pediatric pharmacology. 2021; 18 (2): 110–117. (In Russ.) https://doi.org/10.15690/pf.v18i2.2218.
13. Antonov O.V., Roshchina O. V., Antonova I.V., Ponkrashina, L.P. (2024). Vaccination and immunity: the role of the pediatrician in shaping parents’ commitment to preventive measures. Scientific Bulletin of the Omsk State Medical University. 2024; 4 (2): 20–27. (In Russ.) https://doi.org/10.61634/2782-3024-2024-14-20-27.
14. Galitskaya M.G., Lebedeva A.M., Tkachenko N.E., Makarova S.G. Adherence to vaccination: main trends in modern society. Russian Pediatric Journal. 2022; 25 (4): 253–253. (In Russ.)
15. Kotova P.O. Comparison of vaccination coverage for infants before and during the COVID-19 pandemic. Materials of the X All-Russian Student Scientific and Practical Conference with International participation “Topical Issues of Student Medical Science and Education”, dedicated to the 175th anniversary of the birth of Academician I.P. Pavlov and the 120th anniversary of his Nobel Prize; Riaz State Medical University of the Ministry of Health of the Russian Federation. 2024: 102–103. (In Russ.)
16. Kaur G., Danovaro-Holliday M.C., Mwinnyaa G., et al. Routine Vaccination Coverage — Worldwide, 2022. MMWR Morb Mortal Wkly Rep. 2023; 72 (43): 1155–1161. https://doi.org/10.15585/mmwr.mm7243a1.
17. Liu Y., Bruine de Buin W., Kapteyn A., Szilagyi P.G. Role of Parents’ Perceived Risk and Responsibility in Deciding on Children’s COVID-19 Vaccination. Pediatrics. 2023; 151 (5): e2022058971. https://doi.org/10.1542/peds.2022-058971.
18. Caudal H., Briend-Godet V., Caroff N., et al. Vaccine distrust: Investigation of the views and attitudes of parents in regard to vaccination of their children. Ann Pharm Fr. 2020; 78 (4): 294–302. https://doi.org/10.1016/j.pharma.2020.03.003.
19. Qu S., Yang M., He W., et al. Determinants of parental self-reported uptake of influenza vaccination in preschool children during the COVID-19 pandemic. Hum Vaccin Immunother. 2023; 19 (3): 2268392. https://doi.org/10.1080/21645515.2023.2268392.
20. Isba R., Brennan L., Egboko F., et al. Unmet vaccination need among children under the age of five attending the paediatric emergency department: a cross-sectional study in a large UK district general hospital. BMJ Open. 2023; 13 (6): e072053. https://doi.org/10.1136/bmjopen-2023-072053.
21. Nandi A., Shet A. Why vaccines matter: understanding the broader health, economic, and child development benefits of routine vaccination. Human Vaccines & Immunotherapeutics. 2020; 16 (8): 1900–1904. https://doi.org/10.1080/21645515.2019.1708669.
22. Evdokimova O.V., Afanasyev S.V., Antonova O.A., Konopleva V.I., Gorelov I.S., Kruglova A.P., Biryukov V.V. Study of the main parameters of the immunogenicity of the Ultrix vaccine. I. P. Pavlov Russian Medical Biological Herald. 2020; 28 (1): 21–29. (In Russ.) https://doi.org/10.23888/PAVLOVJ202028121-29.
Review
For citations:
Belykh N.A., Kotova P.O., Pisnyur I.V., Stezhkina E.V. Comparison of vaccination coverage of children of the first year of life in the pre-pandemic period and during the COVID-19 pandemic. Allergology and Immunology in Paediatrics. 2025;(1):40-49. (In Russ.) https://doi.org/10.53529/2500-1175-2025-1-40-49