Buckwheat Protein-Induced Enterocolitis Syndrome: A Series of Clinical Cases
https://doi.org/10.53529/2500-1175-2024-4-63-68
Abstract
Introduction. Case reports of Food Protein-Induced Enterocolitis Syndrome (FPIES) associated with buckwheat consumption are quite rare. However, over the course of 3 years at the Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of Russia, we observed 3 patients who can be considered cases of this rare pathology.
Presentation of the clinical case. The article briefly describes the cases of Food Protein-Induced Enterocolitis Syndrome, associated with consumption of buckwheat porridge, in three patients — 11 months, 7 months, and 7.5 years old. All cases featured an acute form of FPIES of varying severity, with a typical form (absence of specific IgE to buckwheat proteins). The elimination diet excluding the trigger protein was effective in all cases. Two patients were able to reintroduce buckwheat porridge into their diet after 12 months. The 7.5-year-old girl was recommended to continue with the elimination diet for 18 months.
Conclusion. Although buckwheat porridge is generally considered a “hypoallergenic” complementary food, it is important to be aware of the possibility of atypical reactions such as FPIES.
About the Authors
I. G. Gordeeva
National Medical Research Center of Children’s Health of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Irina Grigoryevna Gordeeva — Cand. Sci., Senior Researcher at the Laboratory of Clinical Immunology and Nutritional Science
119296, Moscow, Lomonosovsky Prospect, 2, Building 1
M. G. Galitskaya
National Medical Research Center of Children’s Health of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Marina Gennadyevna Galitskaya — Cand. Sci., Senior Researcher at the Laboratory of Clinical Immunology and Nutritional Science
119296, Moscow, Lomonosovsky Prospect, 2, Building 1
A. A. Galimova
National Medical Research Center of Children’s Health of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Albina Albertovna Galimova — Junior Researcher at the Laboratory of Clinical Immunology and Nutritional Science
119296, Moscow, Lomonosovsky Prospect, 2, Building 1
S. G. Makarova
National Medical Research Center of Children’s Health of the Ministry of Health of the Russian Federation ; Lomonosov Moscow State University
Russian Federation
Russian Federation
Svetlana Gennadyevna Makarova — Dr. Sci., Professor, Deputy Director
119296, Moscow, Lomonosovsky Prospect, 2, Building 1
119991, Moscow, Leninskie Gory 1
A. M. Lebedeva
National Medical Research Center of Children’s Health of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Ayina Mikhailovna Lebedeva — assistant at the Laboratory of Clinical Immunology and Nutritional Science
119296, Moscow, Lomonosovsky Prospect, 2, Building 1
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Review
For citations:
Gordeeva I.G., Galitskaya M.G., Galimova A.A., Makarova S.G., Lebedeva A.M. Buckwheat Protein-Induced Enterocolitis Syndrome: A Series of Clinical Cases. Allergology and Immunology in Paediatrics. 2024;(4):63-68. (In Russ.) https://doi.org/10.53529/2500-1175-2024-4-63-68
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