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Detection of autoantibodies in children with Crohn’s disease depending on the clinical features of the disease

https://doi.org/10.53529/2500-1175-2025-3-115-119

About the Authors

A. A. Zhuzhula
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Anastasia A. Zhuzhula

119991; Lomonosovsky prospect, 2, building 1; Moscow



O. V. Kurbatova
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Olga V. Kurbatova

119991; Lomonosovsky prospect, 2, building 1; Moscow



S. V. Petrichuk
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Svetlana V. Petrichuk

119991; Lomonosovsky prospect, 2, building 1; Moscow



M. A. Snovskaya
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Marina A. Snovskaya

119991; Lomonosovsky prospect, 2, building 1; Moscow



K. A. Mokretsova
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Kadria A. Mokretsova

119991; Lomonosovsky prospect, 2, building 1; Moscow



A. O. Anushenko
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Anton O. Anushenko

119991; Lomonosovsky prospect, 2, building 1; Moscow



E. L. Semikina
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration; The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation
Russian Federation

Elena L. Semikina

119991; Lomonosovsky prospect, 2, building 1; st. Trubetskaya, d. 8, building 2; Moscow



A. S. Potapov
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration; The State Education Institution of Higher Professional Training The First Sechenov Moscow State Medical University under Ministry of Health of the Russian Federation
Russian Federation

Alexander S. Potapov

119991; Lomonosovsky prospect, 2, building 1; st. Trubetskaya, d. 8, building 2; Moscow



A. P. Fisenko
Federal State Autonomous Institution “National Medical Research Center for Children’s Health” of the Ministry of Health of the Russian Fedeeration
Russian Federation

Andrey P. Fisenko

119991; Lomonosovsky prospect, 2, building 1; Moscow



References

1. Svirava A.M., Shiryaeva A.V. Crohn’s disease. Modern methods of diagnosis and treatment. Stolypin Bulletin. 2022; 4 (5): 2721–2739. (In Russ.)

2. Clinical recommendations “Crohn’s Disease” / Approved by the professional association “Union of Pediatricians of Russia”, approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation — 2020. (In Russ.) https://cr.minzdrav.gov.ru/recomend/682_1.

3. Gurina O.P., Stepanova A.A., Dementieva E.A., et al. (2018). Features of autoimmune reactions in children with Crohn’s disease. Clinical Laboratory Diagnostics. 2018; 63 (1): 44–50. (In Russ.) doi: 10.18821.0869-2084-2018-63-1-44-50.

4. Kuznetsova D.A., Lapin S.V., Shchukina O.B. (2020). Diagnostic and prognostic significance of serological markers of inflammatory bowel diseases (literature review). Almanac of Clinical Medicine. 2020; 48 (6): 364–374. (In Russ.) doi: 10.18786/2072-0505-2020-48-061.

5. Aleksandrova E.N., Novikov A.A., Lukina G.V., Parfenov A.I. Clinical value of antibodies in inflammatory bowel diseases.Terapevticheskii arkhiv. 2021; 93 (2): 228–235. (In Russ.) doi: 10.26442/00403660.2021.02.200610.

6. Sendid B., Cornu M., Cordier C., et al. From ASCA breakthrough in Crohn’s disease and Candida albicans research to thirty years of investigations about their meaning in human health. Autoimmun Rev. 2024 Feb; 23 (2): 103486. doi: 10.1016/j.autrev.2023.103486. Epub 2023 Nov 30. PMID: 38040100.

7. Tat’yanina O.F., Potapov A.S., Namazova L.S., Tsimbalova E.G., Kucherenko A., Lokhmatov M. Faecalcalprotectin in noninvasive diagnostics of the inflammatory enteric diseases among children. Pediatric pharmacology. 2008; 5 (3): 46–51. (In Russ.)

8. Tsvetkova V.S., Semikina E.L., Potapov A.S. Biomarkers of inflammatory activity in Crohn’s disease and ulcerative colitis in children. Russian Pediatric Journal. 2021; 24 (S): 64.

9. Zhuzhula A.A., Kurbatova O.V., Petrichuk S.V., et al. Diagnostic significance of the determination of antinuclear antibodies in children with autoimmune hepatitis. Allergology and Immunology in Pediatrics. 2024; (1): 36–40. (In Russ.) doi: 10.53529/2500-1175-2024-1-36-40.


Review

For citations:


Zhuzhula A.A., Kurbatova O.V., Petrichuk S.V., Snovskaya M.A., Mokretsova K.A., Anushenko A.O., Semikina E.L., Potapov A.S., Fisenko A.P. Detection of autoantibodies in children with Crohn’s disease depending on the clinical features of the disease. Allergology and Immunology in Paediatrics. 2025;(3):115-119. (In Russ.) https://doi.org/10.53529/2500-1175-2025-3-115-119

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ISSN 2500-1175 (Print)
ISSN 2712-7958 (Online)