adairАллергология и Иммунология в ПедиатрииAllergology and Immunology in Paediatrics2500-11752712-7958Ассоциация детских аллергологов и иммунологов России10.53529/2500-1175-2022-1-4-15adair-56Research ArticleОБЗОРREVIEWПыльцевая аллергия и пыльцевая сенсибилизация: новый взгляд на старую проблемуPollen allergy and pollen sensitization: a new look at an old subjecthttps://orcid.org/0000-0003-0941-9871МигачёваН. Б.MigachevаN. B.

Наталья Бегиевна Мигачёва, д. м. н., доцент, заведующая кафедрой

кафедра педиатрии ИПО

443056

ул. К. Маркса, 165А

Самара

443056

165A, K. Marks av.

Samara

nbmigacheva@gmail.comФГОУ ВО «Самарский государственный медицинский университет» Министерства здравоохранения Российской ФедерацииSamara State Medical University20222707202301415Copyright © Мигачёва Н.Б., 20232023Мигачёва Н.Б.Migachevа N.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://adair.elpub.ru/jour/article/view/56   Актуальность

   Актуальность. Аллергические заболевания, связанные с гиперчувствительностью к пыльцевым аллергенам (поллинозы), представляют собой актуальную медицинскую и социально-экономическую проблему в связи с повсеместным увеличением распространенности, разнообразием клинических проявлений и негативным влиянием на качество жизни пациентов. Понимание механизмов, лежащих в основе формирования сенсибилизации к аллергенам ветроопыляемых растений, может стать основой для разработки инновационных стратегий лечения и профилактики поллиноза.

   Цель данной статьи

   Цель данной статьи: проанализировать и систематизировать имеющиеся в настоящее время сведения о механизмах формирования пыльцевой сенсибилизации и реализации аллергии на пыльцевые аллергены.

   Relevance. Allergic diseases associated with hypersensitivity to pollen allergens (pollinosis) are an urgent medical and socio-economic problem due to widespread increase in prevalence, a variety of clinical manifestations and a negative impact on the quality of life. Understanding the mechanisms underlying the initiation of sensitization to plant-derived airborne allergens can become the basis for development innovative strategies for the treatment and prevention of hay fever. The aim of the review is to analyze and systematize the currently available data on the mechanisms of the initiation of pollen sensitization and the realization of allergy to pollen allergens.

   The purpose of this article: to systematize the information available today on the influence of the composition of the intestinal microflora on the immunopathogenesis of atopic dermatitis.

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The authors declare that there are no conflicts of interest present.