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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">adair</journal-id><journal-title-group><journal-title xml:lang="ru">Аллергология и Иммунология в Педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Allergology and Immunology in Paediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-1175</issn><issn pub-type="epub">2712-7958</issn><publisher><publisher-name>Ассоциация детских аллергологов и иммунологов России</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">adair-54</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL ARTICLES</subject></subj-group></article-categories><title-group><article-title>ЧАСТОТА ВСТРЕЧАЕМОСТИ НЕАСТМОПОДОБНЫХ СИМПТО-МОВ АЛЛЕРГИЧЕСКИХ ЗАБОЛЕВАНИЙ ПО РЕЗУЛЬТАТАМ ISAAC У ПОДРОСТКОВ ХАБАРОВСКОГО РЕГИОНА, РОССИЯ</article-title><trans-title-group xml:lang="en"><trans-title></trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Супрун</surname><given-names>Евгений Николаевич</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент кафедры госпитальной и факультетской педиатрии с курсом пропедевтики детских болезней ФГБОУ ВО ДВГМУ,  врач аллерголог-иммунолог, старший научный сотрудник группы медико-экологических проблем здоровья матери и ребенка Хабаровского филиала ДНЦ ФПД – НИИ ОМИД</p></bio><email xlink:type="simple">evg-suprun@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Супрун</surname><given-names>Стефания Викторовна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., главный научный сотрудник группы медико-экологических проблем здоровья матери и ребенка Хабаровского филиала ДНЦ ФПД – НИИ ОМИД, профессор кафедры госпитальной и факультетской педиатрии с курсом пропедевтики детских болезней ФГБОУ ВО ДВГМУ, </p></bio><email xlink:type="simple">stefanya-suprun@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шкунова</surname><given-names>Марина Сергеевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач аллерголог-иммунолог</p></bio><email xlink:type="simple">shkunova.marina@mail.ru</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>Евгений Игоревич</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-педиатр</p></bio><email xlink:type="simple">eyakovlev1993@gmail.com</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Телепнева</surname><given-names>Регина Сергеевна</given-names></name></name-alternatives><bio xml:lang="ru"><p>Научный сотрудник Хабаровского филиала ДНЦ ФПД – НИИ ОМИД, врач инфекционист</p></bio><email xlink:type="simple">pupykin84@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лебедько</surname><given-names>Ольга Антоновна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., директор Хабаровского филиала ДНЦ ФПД – НИИ ОМИД, руководитель Лаборатории комплексных методов исследований бронхолегочной и перинатальной патологии НИИ ОМИД</p></bio><email xlink:type="simple">leoaf@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсеева</surname><given-names>Галина Петровна</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., заместитель директора Хабаровского филиала ДНЦ ФПД – НИИ ОМИД по научной работе, главный научный сотрудник группы медико-экологических проблем здоровья матери и ребенка.</p></bio><email xlink:type="simple">evceewa@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>1. Хабаровский филиал Федерального государственного бюджетного научного учреждения «Дальневосточный научный центр физиологии и патологии дыхания – НИИ охраны материнства и детства (Хабаровский филиал ДНЦ ФПД – НИИ ОМИД), (г. Хабаровск)&#13;
2. Федеральной государственное бюджетное образовательное учреждение высшего образования Дальневосточный государственный медицинский университет (ФГБОУ ВО ДВГМУ) (г.Хабаровск)</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>Хабаровский филиал Федерального государственного бюджетного научного учреждения «Дальневосточный научный центр физиологии и патологии дыхания – НИИ охраны материнства и детства (Хабаровский филиал ДНЦ ФПД – НИИ ОМИД), (г. Хабаровск)</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>10</day><month>11</month><year>2023</year></pub-date><volume>0</volume><issue>3</issue><elocation-id>54</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Супрун Е.Н., Супрун С.В., Шкунова М.С., Яковлев Е.И., Телепнева Р.С., Лебедько О.А., Евсеева Г.П., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Супрун Е.Н., Супрун С.В., Шкунова М.С., Яковлев Е.И., Телепнева Р.С., Лебедько О.А., Евсеева Г.П.</copyright-holder><copyright-holder xml:lang="en">Супрун Е.Н., Супрун С.В., Шкунова М.С., Яковлев Е.И., Телепнева Р.С., Лебедько О.А., Евсеева Г.П.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://adair.elpub.ru/jour/article/view/54">https://adair.elpub.ru/jour/article/view/54</self-uri><abstract><sec><title>Введение</title><p>Введение</p><p>В последние десятилетия отмечается рост распространенности бронхиальной астмы у дnетей во всем мире, при этом имеет место значимая разница распространённости астмоподобных симптомов, выявляемых сплошным опросом (ISAAC), и бронхиальной астмы по обращаемости. В ходе стандартизированного опроса ISAAC выявляются не только астмоподобные, но и иные симптомы атопии, распространённость которых в их взаимосвязи с астмоподобными представляет большой интерес для определения вероятности развития БА. В данной работе впервые изучалась частота их встречаемости у школьников Хабаровского края России.</p></sec><sec><title>Материалы и методы </title><p>Материалы и методы </p><p>В опросе участвовали 696 подростков, проживающих в городе Хабаровске и Хабаровском сельском районе, соответствующих требованиям метода программы ISAAC по возрасту (13-14 лет).</p></sec><sec><title>Результаты (Results)</title><p>Результаты (Results):</p><p>Распространённость симптомов аллергического ринита у всех опрашиваемых подростков Хабаровского края составила 69,3%. В группе с астмоподобными симптомами она достоверно больше (77,2% против 56,6%). Осложнения в виде коньюктивита при неинфекционном рините встречались в 12,6% случаев, и так же намного чаще у детей с астмоподобными симптомами (30,1% против 8,9%). Симптомы атопического дерматита встречаются у 11,8% подростков, в 4,6 раза чаще при сочетании с астмоподобными симптомами (22% против 4,8%), локализуются в типичных для атопического дерматита местах – в 5,3% случаев, чаще при наличии астмоподобных симптомов (11,4% против 3,9%).</p></sec><sec><title>Заключение </title><p>Заключение </p><p>Распространённость неастмоподобных симптомов атопии среди подростков Хабаровска и Хабаровского края при изучении методом стандартного сплошного опроса ISAAC выше, чем в большинстве стран, где проводилось данное исследование. Выявленная в ходе опроса частота и структура неастмоподобных симптомов характерна для индустриально развитых стран. Следует отметить, что распространенность и тяжесть неастмоподобных симптомов в городе Хабаровске значительно, выше, чем в Хабаровском сельском районе, однако симптомы неинфекционного ринита на селе протекает тяжелее.</p></sec></abstract><kwd-group xml:lang="ru"><kwd>атопия</kwd><kwd>подростки</kwd><kwd>ISAAC</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">GINA 2018 https://ginasthma.org/wp-content/uploads/2018/04/wms-GINA-2018-report-tracked_v1.3.pdf</mixed-citation><mixed-citation xml:lang="en">GINA 2018 https://ginasthma.org/wp-content/uploads/2018/04/wms-GINA-2018-report-tracked_v1.3.pdf</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Evseeva G.P., Kholodok G.N., Morozova N.V., Suprun E.N., Kozlov V.A., Lazar K.G. Epidemiology of bronchopulmonary diseases in children and adolescents of the Khabarovsk territory. Bulletin of physiology and pathol-ogy of respiration. 2016. Issue 61. – P. 31-35.</mixed-citation><mixed-citation xml:lang="en">Evseeva G.P., Kholodok G.N., Morozova N.V., Suprun E.N., Kozlov V.A., Lazar K.G. Epidemiology of bronchopulmonary diseases in children and adolescents of the Khabarovsk territory. Bulletin of physiology and pathol-ogy of respiration. 2016. Issue 61. – P. 31-35.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">The national program "Bronchial asthma in children. Treatment strategy and prevention". – 5-th ed., reprint. and addit. – Moscow: Original layout, 2017. – 160 p. http://astgmu.ru/wp-content/uploads/2018/10/Natsionalnaya-programma-BA-u-detej.-Strategiya-lecheniya-i-profilaktika.pdf</mixed-citation><mixed-citation xml:lang="en">The national program "Bronchial asthma in children. Treatment strategy and prevention". – 5-th ed., reprint. and addit. – Moscow: Original layout, 2017. – 160 p. http://astgmu.ru/wp-content/uploads/2018/10/Natsionalnaya-programma-BA-u-detej.-Strategiya-lecheniya-i-profilaktika.pdf</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Asthma Insights and Realities in Europe, Chung, K.F. Difficult-to-Treat Severe Asthma / K.F. Chung, E.H. Bel, S.E. Wenzel // European Respirato-ry Society Monograph. – 2011. – Vol. 51. – 310 p.</mixed-citation><mixed-citation xml:lang="en">Asthma Insights and Realities in Europe, Chung, K.F. Difficult-to-Treat Severe Asthma / K.F. Chung, E.H. Bel, S.E. Wenzel // European Respirato-ry Society Monograph. – 2011. – Vol. 51. – 310 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">NHWS-National Health and Wellness Survey https://www.kantarhealth.com/docs/datasheets/kh-national-health-and-wellness-survey.pdf</mixed-citation><mixed-citation xml:lang="en">NHWS-National Health and Wellness Survey https://www.kantarhealth.com/docs/datasheets/kh-national-health-and-wellness-survey.pdf</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Clinical recommendations "Bronchial asthma" Ministry of health of the Russian Federation 2019 http://spulmo.ru/upload/kr_bronhastma_2019.pdf</mixed-citation><mixed-citation xml:lang="en">Clinical recommendations "Bronchial asthma" Ministry of health of the Russian Federation 2019 http://spulmo.ru/upload/kr_bronhastma_2019.pdf</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Arkhipov V.V., Grigorieva E.V., Gavrishina E.V. Control of bronchial asthma in Russia: results of a multicenter observational study of NIKA. // Pulmonology. – 2011. – No. 6. – P. 87-93. [https://doi.org/10.18093/0869-0189-2011-0-6-87-93].</mixed-citation><mixed-citation xml:lang="en">Arkhipov V.V., Grigorieva E.V., Gavrishina E.V. Control of bronchial asthma in Russia: results of a multicenter observational study of NIKA. // Pulmonology. – 2011. – No. 6. – P. 87-93. [https://doi.org/10.18093/0869-0189-2011-0-6-87-93].</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wong GWK, Brunekreef B, Ellwood P, Anderson HR, Asher MI, Crane J, Lai CKW, for the ISAAC Phase Three Study Group. Cooking fuels and prevalence of asthma: a global analysis of phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). //Lancet Resp Med - 2013 - Vol 1. - P. 386-394</mixed-citation><mixed-citation xml:lang="en">Wong GWK, Brunekreef B, Ellwood P, Anderson HR, Asher MI, Crane J, Lai CKW, for the ISAAC Phase Three Study Group. Cooking fuels and prevalence of asthma: a global analysis of phase three of the International Study of Asthma and Allergies in Childhood (ISAAC). //Lancet Resp Med - 2013 - Vol 1. -  P. 386-394</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Weinmayr G., Gehring U., Genuneit J., Büchele G., Kleiner A., Siebers R., Wickens K., Crane J., Brunekreef B., Strachan D. P. The ISAAC Phase Two Study Group Dampness and moulds in relation to respiratory and allergic symptoms in children: results from Phase Two of the Interna-tional Study of Asthma and Allergies in Childhood (ISAAC Phase Two)// Clinical &amp; Experimental Allergy. – 2013 - Vol 1. - P. 762-774</mixed-citation><mixed-citation xml:lang="en">Weinmayr  G., Gehring  U., Genuneit  J., Büchele  G., Kleiner  A., Siebers  R., Wickens  K., Crane  J., Brunekreef  B., Strachan  D. P. The ISAAC Phase Two Study Group Dampness and moulds in relation to respiratory and allergic symptoms in children: results from Phase Two of the Interna-tional Study of Asthma and Allergies in Childhood (ISAAC Phase Two)// Clinical &amp; Experimental Allergy. – 2013 - Vol 1. -  P. 762-774</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Asher M, Keil U, Anderson H, Beasley R, Crane J, Martinez F, et al. Inter-national Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. //European respiratory journal – 1995 – Vol 8(3) – P. 483-91.</mixed-citation><mixed-citation xml:lang="en">Asher M, Keil U, Anderson H, Beasley R, Crane J, Martinez F, et al. Inter-national Study of Asthma and Allergies in Childhood (ISAAC): rationale and methods. //European respiratory journal – 1995 – Vol 8(3) – P. 483-91.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rosa A.M., Ignotti E., Hacon S.S., Castro H.A. Prevalence of asthma in children and adolescents in a city in the Brazilian Amazon region. // Journal Brasil Pneumology. - 2009 – Vol. 35(1) – P. 7-13.</mixed-citation><mixed-citation xml:lang="en">Rosa A.M., Ignotti E., Hacon S.S., Castro H.A. Prevalence of asthma in children and adolescents in a city in the Brazilian Amazon region. // Journal Brasil Pneumology. -  2009 – Vol. 35(1) – P. 7-13.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Nasiri Kalmarzi R, Shekari A, Tajik M, Ataee P, Homagostar Gh, Roshani D, et al. The Prevalence of Asthma Symptoms in Elementary and Middle School Students in Kurdistan Province, the West of Iran. International Jjur-nal of Pediatrics - 2016 – Vol. 4(2) P. 1323-30.</mixed-citation><mixed-citation xml:lang="en">Nasiri Kalmarzi R, Shekari A, Tajik M, Ataee P, Homagostar Gh, Roshani D, et al. The Prevalence of Asthma Symptoms in Elementary and Middle School Students in Kurdistan Province, the West of Iran. International Jjur-nal of Pediatrics - 2016 – Vol. 4(2) P. 1323-30.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Suprun E., Suprun S., Shkunova M., Yakovlev E.I., Evseeva G.P., Lebedko O.A. Incidence of asthma-like symptoms in adolescents of khabarovsk and the Khabarovsk rural area, Russian Federation. International Journal of Pe-diatrics. 2020. Т. 8. № 12. P. 12697-12704.</mixed-citation><mixed-citation xml:lang="en">Suprun E., Suprun S., Shkunova M., Yakovlev E.I., Evseeva G.P., Lebedko O.A. Incidence of asthma-like symptoms in adolescents of khabarovsk and the Khabarovsk rural area, Russian Federation. International Journal of Pe-diatrics. 2020. Т. 8. № 12. P. 12697-12704.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Glushkova A.V., Grjibovski A.M. Prevalence and Correlates of Asthma Among Children in Central St.Petersburg, Russia: Cross-sectional Study// Croat Med Journal – 2008 – Vol.49 – P.741-50.</mixed-citation><mixed-citation xml:lang="en">Glushkova A.V., Grjibovski A.M. Prevalence and Correlates of Asthma Among Children in Central St.Petersburg, Russia: Cross-sectional Study// Croat Med Journal – 2008 – Vol.49 – P.741-50.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kamaltynova Ye.M., Deyev I.A., Belonogova Ye.G. Comparative epide-miological characteristics of bronchial asthma according to data of Interna-tional Study of Asthma and Allergy in Childhood (ISAAC) // Bulletin of Siberian medicine. 2009. No. 4. – P. 92-98.</mixed-citation><mixed-citation xml:lang="en">Kamaltynova Ye.M., Deyev I.A., Belonogova Ye.G. Comparative epide-miological characteristics of bronchial asthma according to data of Interna-tional Study of Asthma and Allergy in Childhood (ISAAC) // Bulletin of Siberian medicine. 2009. No. 4. – P. 92-98.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Batozhargalova B.Ts., Mizernitsky Yu.L., Podolnaya M.A. Meta-analysis of the prevalence of asthma-like symptoms and bronchial asthma in Russia (based on the results of the ISAAC program). Russian Bulletin of Perina-tology and Pediatrics. 2016. 61(4). – P. 59-69. DOI: 10.21508/1027-4065-2016-61-4-59-69</mixed-citation><mixed-citation xml:lang="en">Batozhargalova B.Ts., Mizernitsky Yu.L., Podolnaya M.A. Meta-analysis of the prevalence of asthma-like symptoms and bronchial asthma in Russia (based on the results of the ISAAC program). Russian Bulletin of Perina-tology and Pediatrics. 2016. 61(4). – P. 59-69. DOI: 10.21508/1027-4065-2016-61-4-59-69</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bragina E.Yu., Freidin M.B., Puzyrev V.P. Genetics of «atopic march» syntropy. Siberian Scientific Medical Journal. 2020; 40 (5): 4–17. [In Rus-sian]. doi: 10.15372/SSMJ20200501</mixed-citation><mixed-citation xml:lang="en">Bragina E.Yu., Freidin M.B., Puzyrev V.P. Genetics of «atopic march» syntropy. Siberian Scientific Medical Journal. 2020; 40 (5): 4–17. [In Rus-sian]. doi: 10.15372/SSMJ20200501</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Martín Fernández-Mayoralas D, Martín Caballero JM, García-Marcos Al-varez L. Asociación entre dermatitis atópica, rinitis alérgica y asma en esco-lares de 13 y 14 años [Association between atopic dermatitis, allergic rhini-tis and asthma in schoolchildren aged 13-14 years old]. An Pediatr (Barc). 2004 Mar;60(3):236-42. Spanish. doi: 10.1016/s1695-4033(04)78257-0. PMID: 14987514.</mixed-citation><mixed-citation xml:lang="en">Martín Fernández-Mayoralas D, Martín Caballero JM, García-Marcos Al-varez L. Asociación entre dermatitis atópica, rinitis alérgica y asma en esco-lares de 13 y 14 años [Association between atopic dermatitis, allergic rhini-tis and asthma in schoolchildren aged 13-14 years old]. An Pediatr (Barc). 2004 Mar;60(3):236-42. Spanish. doi: 10.1016/s1695-4033(04)78257-0. PMID: 14987514.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Eder W, Gamper A, Oberfeld G, Riedler J. Prävalenz und Schweregrad von Asthma bronchiale, allergischer Rhinitis und atopischer Dermatitis bei Salzburger Schulkindern [Prevalence and severity of bronchial asthma, al-lergic rhinitis and atopic dermatitis in Salzburg school children]. Wien Klin Wochenschr. 1998 Oct 16;110(19):669-77. German. PMID: 9823620.</mixed-citation><mixed-citation xml:lang="en">Eder W, Gamper A, Oberfeld G, Riedler J. Prävalenz und Schweregrad von Asthma bronchiale, allergischer Rhinitis und atopischer Dermatitis bei Salzburger Schulkindern [Prevalence and severity of bronchial asthma, al-lergic rhinitis and atopic dermatitis in Salzburg school children]. Wien Klin Wochenschr. 1998 Oct 16;110(19):669-77. German. PMID: 9823620.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Montefort S, Lenicker HM, Caruna S, Agius Muscat H. Asthma, rhinitis and eczema in Maltese 13-15 year-old schoolchildren -- prevalence, severi-ty and associated factors [ISAAC]. International Study of Asthma and Al-lergies in Childhood. Clin Exp Allergy. 1998 Sep;28(9):1089-99. doi: 10.1046/j.1365-2222.1998.00350.x. PMID: 9761012.</mixed-citation><mixed-citation xml:lang="en">Montefort S, Lenicker HM, Caruna S, Agius Muscat H. Asthma, rhinitis and eczema in Maltese 13-15 year-old schoolchildren -- prevalence, severi-ty and associated factors [ISAAC]. International Study of Asthma and Al-lergies in Childhood. Clin Exp Allergy. 1998 Sep;28(9):1089-99. doi: 10.1046/j.1365-2222.1998.00350.x. PMID: 9761012.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Falade AG, Olawuyi F, Osinusi K, Onadeko BO. Prevalence and severity of symptoms of asthma, allergic rhino-conjunctivitis and atopic eczema in secondary school children in Ibadan, Nigeria. East Afr Med J. 1998 Dec;75(12):695-8. PMID: 10065208. Waked M, Salameh P. Asthma, aller-gic rhinitis and eczema in 13-14-year-old schoolchildren across Lebanon. J Med Liban. 2006 Oct-Dec;54(4):181-90. PMID: 17330369.</mixed-citation><mixed-citation xml:lang="en">Falade AG, Olawuyi F, Osinusi K, Onadeko BO. Prevalence and severity of symptoms of asthma, allergic rhino-conjunctivitis and atopic eczema in secondary school children in Ibadan, Nigeria. East Afr Med J. 1998 Dec;75(12):695-8. PMID: 10065208. Waked M, Salameh P. Asthma, aller-gic rhinitis and eczema in 13-14-year-old schoolchildren across Lebanon. J Med Liban. 2006 Oct-Dec;54(4):181-90. PMID: 17330369.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Phathammavong O, Ali M, Phengsavanh A, Xaysomphou D, Odajima H, Nishima S, Kuroiwa C. Prevalence and potential risk factors of rhinitis and atopic eczema among schoolchildren in Vientiane capital, Lao PDR: ISAAC questionnaire. Biosci Trends. 2008 Oct;2(5):193-9. PMID: 20103927.</mixed-citation><mixed-citation xml:lang="en">Phathammavong O, Ali M, Phengsavanh A, Xaysomphou D, Odajima H, Nishima S, Kuroiwa C. Prevalence and potential risk factors of rhinitis and atopic eczema among schoolchildren in Vientiane capital, Lao PDR: ISAAC questionnaire. Biosci Trends. 2008 Oct;2(5):193-9. PMID: 20103927.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Ece A, Ceylan A, Saraçlar Y, Saka G, Gürkan F, Haspolat K. Prevalence of asthma and other allergic disorders among schoolchildren in Diyarbakir, Turkey. Turk J Pediatr. 2001 Oct-Dec;43(4):286-92. PMID: 11765156.</mixed-citation><mixed-citation xml:lang="en">Ece A, Ceylan A, Saraçlar Y, Saka G, Gürkan F, Haspolat K. Prevalence of asthma and other allergic disorders among schoolchildren in Diyarbakir, Turkey. Turk J Pediatr. 2001 Oct-Dec;43(4):286-92. PMID: 11765156.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Solis Soto MT, Patiño A, Nowak D, Radon K. Prevalence of asthma, rhini-tis and eczema symptoms in rural and urban school-aged children from Oropeza Province - Bolivia: a cross-sectional study. BMC Pulm Med. 2014 Mar 10;14:40. doi: 10.1186/1471-2466-14-40. PMID: 24612913; PMCID: PMC3975636.</mixed-citation><mixed-citation xml:lang="en">Solis Soto MT, Patiño A, Nowak D, Radon K. Prevalence of asthma, rhini-tis and eczema symptoms in rural and urban school-aged children from Oropeza Province - Bolivia: a cross-sectional study. BMC Pulm Med. 2014 Mar 10;14:40. doi: 10.1186/1471-2466-14-40. PMID: 24612913; PMCID: PMC3975636.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hasnain SM, Khan M, Saleem A, Waqar MA. Prevalence of asthma and al-lergic rhinitis among school children of Karachi, Pakistan, 2007. J Asthma. 2009 Feb;46(1):86-90. doi: 10.1080/02770900802513023. PMID: 19191144.</mixed-citation><mixed-citation xml:lang="en">Hasnain SM, Khan M, Saleem A, Waqar MA. Prevalence of asthma and al-lergic rhinitis among school children of Karachi, Pakistan, 2007. J Asthma. 2009 Feb;46(1):86-90. doi: 10.1080/02770900802513023. PMID: 19191144.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao T, Wang HJ, Chen Y, Xiao M, Duo L, Liu G, Lau Y, Karlberg J. Prevalence of childhood asthma, allergic rhinitis and eczema in Urumqi and Beijing. J Paediatr Child Health. 2000 Apr;36(2):128-33. doi: 10.1046/j.1440-1754.2000.00457.x. Erratum in: J Paediatr Child Health. J Paediatr Child Health. 2003 Jul;39(5):397. Wang, A [corrected to Wang, HJ]. PMID: 10760010.</mixed-citation><mixed-citation xml:lang="en">Zhao T, Wang HJ, Chen Y, Xiao M, Duo L, Liu G, Lau Y, Karlberg J. Prevalence of childhood asthma, allergic rhinitis and eczema in Urumqi and Beijing. J Paediatr Child Health. 2000 Apr;36(2):128-33. doi: 10.1046/j.1440-1754.2000.00457.x. Erratum in: J Paediatr Child Health. J Paediatr Child Health. 2003 Jul;39(5):397. Wang, A [corrected to Wang, HJ]. PMID: 10760010.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Farrokhi S, Gheybi MK, Movahhed A, Dehdari R, Gooya M, Keshvari S, Gholampour H, Mansourian Z, Khosravi Y, Ghahramani F, Zandi S, Etemadan R, Tahmasebi R, Reaisi A, Keshmiri S, Fadaizadeh L, Masjedi MR. Prevalence and risk factors of asthma and allergic diseases in primary schoolchildren living in Bushehr, Iran: phase I, III ISAAC protocol. Iran J Allergy Asthma Immunol. 2014 Oct;13(5):348-55. PMID: 25150076.</mixed-citation><mixed-citation xml:lang="en">Farrokhi S, Gheybi MK, Movahhed A, Dehdari R, Gooya M, Keshvari S, Gholampour H, Mansourian Z, Khosravi Y, Ghahramani F, Zandi S, Etemadan R, Tahmasebi R, Reaisi A, Keshmiri S, Fadaizadeh L, Masjedi MR. Prevalence and risk factors of asthma and allergic diseases in primary schoolchildren living in Bushehr, Iran: phase I, III ISAAC protocol. Iran J Allergy Asthma Immunol. 2014 Oct;13(5):348-55. PMID: 25150076.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Zivković Z, Vukašinović Z, Cerović S, Radulović S, Zivanović S, Panić E, Hadnadjev M, Adžović O. Prevalence of childhood asthma and allergies in Serbia and Montenegro. World J Pediatr. 2010 Nov;6(4):331-6. doi: 10.1007/s12519-010-0207-y. Epub 2010 Jun 12. PMID: 20549414.</mixed-citation><mixed-citation xml:lang="en">Zivković Z, Vukašinović Z, Cerović S, Radulović S, Zivanović S, Panić E, Hadnadjev M, Adžović O. Prevalence of childhood asthma and allergies in Serbia and Montenegro. World J Pediatr. 2010 Nov;6(4):331-6. doi: 10.1007/s12519-010-0207-y. Epub 2010 Jun 12. PMID: 20549414.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Teeratakulpisarn J, Wiangnon S, Kosalaraksa P, Heng S. Surveying the prevalence of asthma, allergic rhinitis and eczema in school-children in Khon Kaen, Northeastern Thailand using the ISAAC questionnaire: phase III. Asian Pac J Allergy Immunol. 2004 Dec;22(4):175-81. PMID: 15783129.</mixed-citation><mixed-citation xml:lang="en">Teeratakulpisarn J, Wiangnon S, Kosalaraksa P, Heng S. Surveying the prevalence of asthma, allergic rhinitis and eczema in school-children in Khon Kaen, Northeastern Thailand using the ISAAC questionnaire: phase III. Asian Pac J Allergy Immunol. 2004 Dec;22(4):175-81. PMID: 15783129.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Amarasekera ND, Gunawardena NK, de Silva NR, Weerasinghe A. Preva-lence of childhood atopic diseases in the Western Province of Sri Lanka. Ceylon Med J. 2010 Mar;55(1):5-8. doi: 10.4038/cmj.v55i1.1700. PMID: 20446533.</mixed-citation><mixed-citation xml:lang="en">Amarasekera ND, Gunawardena NK, de Silva NR, Weerasinghe A. Preva-lence of childhood atopic diseases in the Western Province of Sri Lanka. Ceylon Med J. 2010 Mar;55(1):5-8. doi: 10.4038/cmj.v55i1.1700. PMID: 20446533.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Kabir ML, Rahman F, Hassan MQ, Ahamed F, Mridha MA. Asthma, atop-ic eczema and allergic rhino-conjunctivitis in school children. Mymensingh Med J. 2005 Jan;14(1):41-5. PMID: 15695953.</mixed-citation><mixed-citation xml:lang="en">Kabir ML, Rahman F, Hassan MQ, Ahamed F, Mridha MA. Asthma, atop-ic eczema and allergic rhino-conjunctivitis in school children. Mymensingh Med J. 2005 Jan;14(1):41-5. PMID: 15695953.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Quah BS, Razak AR, Hassan MH. Prevalence of asthma, rhinitis and ecze-ma among schoolchildren in Kelantan, Malaysia. Acta Paediatr Jpn. 1997 Jun;39(3):329-35. doi: 10.1111/j.1442-200x.1997.tb03746.x. PMID: 9241894.</mixed-citation><mixed-citation xml:lang="en">Quah BS, Razak AR, Hassan MH. Prevalence of asthma, rhinitis and ecze-ma among schoolchildren in Kelantan, Malaysia. Acta Paediatr Jpn. 1997 Jun;39(3):329-35. doi: 10.1111/j.1442-200x.1997.tb03746.x. PMID: 9241894.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Rahimi Rad MH, Hejazi ME, Behrouzian R. Asthma and other allergic dis-eases in 13-14-year-old schoolchildren in Urmia, Iran. [corrected]. East Mediterr Health J. 2007 Sep-Oct;13(5):1005-16. doi: 10.26719/2007.13.5.1005. Erratum in: East Mediterr Health J. 2009 Nov-Dec;15(6):1364. PMID: 18290392.</mixed-citation><mixed-citation xml:lang="en">Rahimi Rad MH, Hejazi ME, Behrouzian R. Asthma and other allergic dis-eases in 13-14-year-old schoolchildren in Urmia, Iran. [corrected]. East Mediterr Health J. 2007 Sep-Oct;13(5):1005-16. doi: 10.26719/2007.13.5.1005. Erratum in: East Mediterr Health J. 2009 Nov-Dec;15(6):1364. PMID: 18290392.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Solé D, Cassol VE, Silva AR, Teche SP, Rizzato TM, Bandim LC, Sarinho ES, Camelo-Nunes IC. Prevalence of symptoms of asthma, rhinitis, and atopic eczema among adolescents living in urban and rural areas in different regions of Brazil. Allergol Immunopathol (Madr). 2007 Nov-Dec;35(6):248-53. doi: 10.1157/13112991. PMID: 18047816.</mixed-citation><mixed-citation xml:lang="en">Solé D, Cassol VE, Silva AR, Teche SP, Rizzato TM, Bandim LC, Sarinho ES, Camelo-Nunes IC. Prevalence of symptoms of asthma, rhinitis, and atopic eczema among adolescents living in urban and rural areas in different regions of Brazil. Allergol Immunopathol (Madr). 2007 Nov-Dec;35(6):248-53. doi: 10.1157/13112991. PMID: 18047816.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Standardized epidemiology researches of allergic diseases for children. Ad-aptation of the program «International research of asthma and allergy for children («ISAAC») in Russia. Moscow, 1998; 30</mixed-citation><mixed-citation xml:lang="en">Standardized epidemiology researches of allergic diseases for children. Ad-aptation of the program «International research of asthma and allergy for children («ISAAC») in Russia. Moscow, 1998; 30</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Brożek JL, Bousquet J, Agache I, Agarwal A, Bachert C, Bosnic-Anticevich S, Brignardello-Petersen R, Canonica GW, Casale T, Cha-vannes NH, Correia de Sousa J, Cruz AA, Cuello-Garcia CA, Demoly P, Dykewicz M, Etxeandia-Ikobaltzeta I, Florez ID, Fokkens W, Fonseca J, Hellings PW, Klimek L, Kowalski S, Kuna P, Laisaar K-T, Larenas-Linnemann DE, Lødrup Carlsen KC, Manning PJ, Meltzer E, Mullol J, Muraro A, O’Hehir R, Ohta K, Panzner P, Papadopoulos N, Park H-S, Pas-salacqua G, Pawankar R, Price D, Riva JJ, Roldán Y, Ryan D, Sadeghirad B, Samolinski B, Schmid-Grendelmeier P, Sheikh A, Togias A, Valero A, Valiulis A, Valovirta E, Ventresca M, Wallace D, Waserman S, Wickman M, Wiercioch W, Yepes-Nuñez JJ, Zhang L, Zhang Y, Zidarn M, Zuberbier T, Schünemann HJ, Allergic Rhinitis and its Impact on Asthma (ARIA) Guidelines – 2016 Revision, Journal of Allergy and Clinical Immunology (2017), doi: 10.1016/j.jaci.2017.03.050.</mixed-citation><mixed-citation xml:lang="en">Brożek JL, Bousquet J, Agache I, Agarwal A, Bachert C, Bosnic-Anticevich S, Brignardello-Petersen R, Canonica GW, Casale T, Cha-vannes NH, Correia de Sousa J, Cruz AA, Cuello-Garcia CA, Demoly P, Dykewicz M, Etxeandia-Ikobaltzeta I, Florez ID, Fokkens W, Fonseca J, Hellings PW, Klimek L, Kowalski S, Kuna P, Laisaar K-T, Larenas-Linnemann DE, Lødrup Carlsen KC, Manning PJ, Meltzer E, Mullol J, Muraro A, O’Hehir R, Ohta K, Panzner P, Papadopoulos N, Park H-S, Pas-salacqua G, Pawankar R, Price D, Riva JJ, Roldán Y, Ryan D, Sadeghirad B, Samolinski B, Schmid-Grendelmeier P, Sheikh A, Togias A, Valero A, Valiulis A, Valovirta E, Ventresca M, Wallace D, Waserman S, Wickman M, Wiercioch W, Yepes-Nuñez JJ, Zhang L, Zhang Y, Zidarn M, Zuberbier T, Schünemann HJ, Allergic Rhinitis and its Impact on Asthma (ARIA) Guidelines – 2016 Revision, Journal of Allergy and Clinical Immunology (2017), doi: 10.1016/j.jaci.2017.03.050.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Shamssain MH, Shamsian N. Prevalence and severity of asthma, rhinitis, and atopic eczema in 13- to 14-year-old schoolchildren from the northeast of England. Ann Allergy Asthma Immunol. 2001 Apr;86(4):428-32. doi: 10.1016/S1081-1206(10)62490-8. PMID: 11345287.</mixed-citation><mixed-citation xml:lang="en">Shamssain MH, Shamsian N. Prevalence and severity of asthma, rhinitis, and atopic eczema in 13- to 14-year-old schoolchildren from the northeast of England. Ann Allergy Asthma Immunol. 2001 Apr;86(4):428-32. doi: 10.1016/S1081-1206(10)62490-8. PMID: 11345287.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">John Asekhaen Ohiolei, Clement Isaac, Oriri Asemota Omorodion A re-view of soil transmitted helminthiasis in Nigeria. Asian Pacific Journal of Tropical Disease. 2017; 7(12): 841-848</mixed-citation><mixed-citation xml:lang="en">John Asekhaen Ohiolei, Clement Isaac, Oriri Asemota Omorodion A re-view of soil transmitted helminthiasis in Nigeria. Asian Pacific Journal of Tropical Disease. 2017; 7(12): 841-848</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
