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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">adair</journal-id><journal-title-group><journal-title xml:lang="ru">Аллергология и Иммунология в Педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Allergology and Immunology in Paediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-1175</issn><issn pub-type="epub">2712-7958</issn><publisher><publisher-name>Ассоциация детских аллергологов и иммунологов России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.53529/2500-1175-2024-4-4-13</article-id><article-id custom-type="elpub" pub-id-type="custom">adair-175</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Патогенез и клинические симптомы острых проявлений пищевой аллергии у детей</article-title><trans-title-group xml:lang="en"><trans-title>Pathogenesis and clinical symptoms of acute manifestations of food allergy in children</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0716-3529</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лепешкова</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Lepeshkova</surname><given-names>T. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лепешкова Татьяна Сергеевна — д. м. н., врач аллерголог-иммунолог, доцент кафедры поликлинической педиатрии  </p><p>г. Екатеринбург, 620028, ул. Репина, 3 </p></bio><bio xml:lang="en"><p>Lepeshkova Tatiana Sergeevna — Dr. Sci, associate professor of polyclinic Pediatrics  </p><p>Yekaterinburg, 620028, Repina str., 3 </p></bio><email xlink:type="simple">evlpa@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации<country>Россия</country></aff><aff xml:lang="en">Federal State Budgetary Educational Institution of Higher Professional Education “The Urals State Medical University” of the Ministry of Health of Russia<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>22</day><month>01</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>4</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лепешкова Т.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Лепешкова Т.С.</copyright-holder><copyright-holder xml:lang="en">Lepeshkova T.S.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://adair.elpub.ru/jour/article/view/175">https://adair.elpub.ru/jour/article/view/175</self-uri><abstract><sec><title>Введение</title><p>Введение. Аллергические реакции у детей широко распространены и нередко возникают на продукты питания. Немедленные IgE-опосредованные проявления пищевой аллергии доставляют много переживаний и неприятностей пациентам и медицинскому персоналу, поскольку возникают остро и в ряде случаев становятся причиной системных генерализованных проявлений.</p></sec><sec><title>Цель обзора</title><p>Цель обзора: в доступной для практикующих врачей форме представить данные по патогенезу и клиническим симптомам острых проявлений пищевой аллергии и рассмотреть варианты их терапии.</p></sec><sec><title>Заключение</title><p>Заключение. Знание патогенеза IgE-опосредованных реакций необходимо любому практикующему врачу для выбора правильной врачебной тактики и купирования неотложных реакций.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Allergic reactions in children are widespread and often occur to food products. Immediate IgE-mediated manifestations of food allergies cause a lot of worries and troubles for patients and medical personnel, since they occur acutely and, in some cases, cause systemic generalized manifestations.</p><p>The aim of the review is to present data on the pathogenesis and clinical symptoms of acute manifestations of food allergy and to consider options for their treatment.</p></sec><sec><title>Conclusions</title><p>Conclusions. Knowledge of the pathogenesis of IgE-mediated reactions is necessary for any practicing doctor to choose the correct medical tactics and stop emergency reactions.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>дети</kwd><kwd>пищевая аллергия</kwd><kwd>пищевая анафилаксия</kwd><kwd>синдром оральной аллергии</kwd></kwd-group><kwd-group xml:lang="en"><kwd>children</kwd><kwd>food allergy</kwd><kwd>food anaphylaxis</kwd><kwd>oral allergy syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Boyce J.A., Assa’a A., Burks A.W. [et al.]. Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. Nutrition. 2011; 27 (2): 253–267. https://doi.org/10.1016/j.nut.2010.12.001.</mixed-citation><mixed-citation xml:lang="en">Boyce J.A., Assa’a A., Burks A.W. [et al.]. 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