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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">adair</journal-id><journal-title-group><journal-title xml:lang="ru">Аллергология и Иммунология в Педиатрии</journal-title><trans-title-group xml:lang="en"><trans-title>Allergology and Immunology in Paediatrics</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2500-1175</issn><issn pub-type="epub">2712-7958</issn><publisher><publisher-name>Ассоциация детских аллергологов и иммунологов России</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.53529/2500-1175-2024-2-18-25</article-id><article-id custom-type="elpub" pub-id-type="custom">adair-143</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОР</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEW</subject></subj-group></article-categories><title-group><article-title>Новые возможности аллерген-специфической иммунотерапии в отношении индукции противовирусного иммунитета у пациентов с бронхиальной астмой</article-title><trans-title-group xml:lang="en"><trans-title>New possibilities of allergen-specific immunotherapy in relation to the induction of antiviral immunity in patients with bronchial asthma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7964-8867</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Максимова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Maksimova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Максимова Анна Владимировна — врач аллерголог-иммунолог, педиатр, к. м. н., доцент кафедры клинической иммунологии, аллергологии и адаптологии факультета непрерывного медицинского образования медицинского института РУДН им. Патриса Лумумбы; ведущий специалист ИАКИ.</p><p>117198, Москва, ул. Миклухо-Маклая, 6; Москва, ул. Малая Бронная, 20, стр. 1</p></bio><bio xml:lang="en"><p>Anna V. Maksimova - allergist-immunologist, pediatrician, candidate of medical sciences, Associate Professor of the Department of Clinical Immunology, Allergology and Adaptology, Faculty of Continuing Medical Education, Medical Institute, Patrice Lumumba Peoples’ Friendship University of Russia; Leading specialist of the Institute of Allergy and Clinical Immunology LLC (IACI).</p><p>117198, Moscow, st. Miklouho-Maclay, 6; Moscow, st. Malaya Bronnaya, 20/1</p></bio><email xlink:type="simple">minaeva.a.v@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Российский университет дружбы народов им. Патриса Лумумбы; ООО «Институт аллергологии и клинической иммунологии» (ИАКИ)<country>Россия</country></aff><aff xml:lang="en">Patrice Lumumba Peoples’ Friendship University of Russia; Institute of Allergy and Clinical Immunology LLC (IACI)<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>24</day><month>06</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>18</fpage><lpage>25</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Максимова А.В., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Максимова А.В.</copyright-holder><copyright-holder xml:lang="en">Maksimova A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://adair.elpub.ru/jour/article/view/143">https://adair.elpub.ru/jour/article/view/143</self-uri><abstract><sec><title>Актуальность</title><p>Актуальность. В обзоре рассмотрены современные представления о иммуномодулирующем эффекте аллерген-специфической иммунотерапии в отношении повышения резистентности к инфекционным патогенам. Изложенная информация позволит клиницистам более осознанно подходить к процессу планирования терапии бронхиальной астмы, рассматривая аллерген-специфическую иммунотерапию не только как инструмент патогенетического лечения причинно-значимой сенсибилизации, но и как инструмент иммуномодулирующей терапии в отношении респираторных вирусных инфекций.</p></sec><sec><title>Цель работы</title><p>Цель работы: систематизация накопленного опыта с целью предоставления информации для практикующего врача.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Relevance</title><p>Relevance. The review examines modern ideas about the immunomodulatory effect of allergen-specific immunotherapy in relation to increasing resistance to infectious pathogens. The information presented will allow clinicians to take a more conscious approach to the process of planning therapy for bronchial asthma, considering allergen-specific immunotherapy not only as a tool for pathogenetic treatment of causally significant sensitization, but also as a tool for immunomodulatory therapy against respiratory viral infections.</p></sec><sec><title>Purpose of the work</title><p>Purpose of the work: systematization of accumulated experience in order to provide information for the practicing physician.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>аллерген-специфическая иммунотерапия</kwd><kwd>IL-6</kwd><kwd>IL-33</kwd><kwd>ИФН-β</kwd><kwd>вирусная инфекция</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bronchial asthma</kwd><kwd>allergen-specific immunotherapy</kwd><kwd>IL-6</kwd><kwd>IL-33</kwd><kwd>IFN-β</kwd><kwd>viral infection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Papadopoulos NG, Psarras S, Manoussakis E, Saxoni-Papageorgiou P. 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